Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC3319
Trial ID NCT05698303
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CT103A
Generation2nd
PhasePhase1
Recruitment statusNot Recruiting
TitleA Study of Fully Human BCMA Chimeric Antigen Receptor Autologous T Cell Injection (CT103A) in the Treatment of Patients With Relapsed/Refractory Multiple Myeloma
Year2023
CountryUnited States
Company sponsorNanjing IASO Biotherapeutics Co., Ltd
Other ID(s)CT103AA001
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes

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