Gene symbol | ROR1 | Synonyms | NTRKR1, dJ537F10.1 | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1p31.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | receptor tyrosine kinase like orphan receptor 1 |
GTO ID | GTC3317 |
Trial ID | NCT05694364 |
Disease | Diffuse Large B-Cell Lymphoma | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Triple-Receptor Negative Breast Cancer | Chronic Lymphocytic Leukemia |
Altered gene | ROR1 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | PRGN-3007 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Dose Escalation/Dose Expansion Study of PRGN-3007 UltraCAR-T Cells in Patients With Advanced Hematologic and Solid Tumor Malignancies |
Year | 2023 |
Country | United States |
Company sponsor | H. Lee Moffitt Cancer Center and Research Institute |
Other ID(s) | MCC-21622|PRGN-3007 |
Vector information | |||||
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Cohort 1 | |||||||||||
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