Basic Information

Gene symbol DLL3 Synonyms SCDO1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description delta like canonical Notch ligand 3

GTO ID GTC3305
Trial ID NCT05680922
Disease Lung Small Cell Carcinoma | Large Cell Neuroendocrine Carcinoma
Altered gene DLL3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment LB2102
Generation2nd
PhasePhase1
Recruitment statusNot Recruiting
TitleDLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer
Year2023
CountryUnited States
Company sponsorLegend Biotech USA Inc
Other ID(s)LB2102-1001

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 41
Age Adult, Older_Adult

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