Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC3300 |
Trial ID | NCT05674175 |
Disease | T Cell Lymphoblastic Lymphoma | B-Cell Acute Lymphoblastic Leukemia |
Altered gene | CD19|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T22-65s|CD19 CAR-T cells |
Generation | 2nd |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | Co-administration of CART22-65s and huCART19 for B-ALL |
Year | 2023 |
Country | United States |
Company sponsor | Stephan Grupp MD PhD |
Other ID(s) | 22-020640|22CT015 |
Cohort 1 | |||||||||
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