Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3300
Trial ID NCT05674175
Disease T Cell Lymphoblastic Lymphoma | B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T22-65s|CD19 CAR-T cells
Generation2nd
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleCo-administration of CART22-65s and huCART19 for B-ALL
Year2023
CountryUnited States
Company sponsorStephan Grupp MD PhD
Other ID(s)22-020640|22CT015

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 93
Age Child, Adult

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