Basic Information

Gene symbol TM4SF1 Synonyms H-L6, L6, M3S1, TAAL6 Type of gene protein-coding
Description transmembrane 4 L six family member 1

GTO ID GTC3298
Trial ID NCT05673434
Disease Digestive Tumor
Altered gene TM4SF1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment TM4SF1 CAR-T cells
Recruitment statusNot Recruiting
TitleA Clinical Study on the Safety and Efficacy of CAR-T Therapy for the TM4SF1-positive Tumors of Digestive System
Year2023
CountryChina
Company sponsorChanghai Hospital
Other ID(s)CART-TM4SF1-01

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5~1E6 cells/kg, 1~2E6 cells/kg, 2~3E6 cells/kg, 3~10E6 cells/kg
Pts 24
Age Adult, Older_Adult

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