Basic Information

Gene symbol HLA-G Synonyms MHC-G Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description major histocompatibility complex, class I, G

GTO ID GTC3297
Trial ID NCT05672459
Disease Solid Tumor
Altered gene HLA-G
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment IVS-3001
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Safety And Efficacy Study Of HLA-G- Targeted CAR-T Cells IVS-3001 In Subjects With Previously Treated Advanced HLA-G-Positive Solid Tumors
Year2023
CountryUnited States
Company sponsorM.D. Anderson Cancer Center
Other ID(s)2022-0261|NCI-2023-00020

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 117
Age Adult, Older_Adult
Lymph depletion Yes

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