Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3273
Trial ID NCT05651100
Disease B-Cell Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleSafety and Efficacy of Sequential CD19 and CD22 Targeted CAR-T Therapy for Relapsed/Refractory B Cell Lymphoma
Year2022
CountryChina
Company sponsorKecellitics Biotech Company Ltd
Other ID(s)Kece-4

Clinical Result

Cohort 1
Administration route None
Pts 50
Age Child, Adult, Older_Adult
Lymph depletion Yes

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