Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3265
Trial ID NCT05643742
Disease Mantle Cell Lymphoma | B-Cell Lymphoma | Non-Hodgkin's Lymphoma | Follicular Lymphoma | Large B-Cell Lymphoma | Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | Marginal Zone Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CTX112
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies
Year2022
CountryUnited States
Company sponsorCRISPR Therapeutics AG
Other ID(s)CRSP-ONC-006

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Allogeneic
Pts 120
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph