Basic Information

Gene symbol NRARP Synonyms None Type of gene protein-coding
Description NOTCH regulated ankyrin repeat protein

GTO ID GTC3258
Trial ID NCT05637255
Disease Age-Related Macular Degeneration | Macular Degeneration
Altered gene NRARP
Therapeutic/Target gene Target gene
TherapysiRNA
Treatment SYL1801
PhasePhase2
Recruitment statusRecruiting
TitleA Randomized, Double Masked, Parallel Group, Dose-finding Study to Evaluate SYL1801 in Patients With Neovascular AMD
Year2022
CountryCzechia|Poland|Slovakia
Company sponsorSylentis, S.A.
Other ID(s)SYL1801_II|2022-000214-34

Clinical Result

Cohort1: Low Dose
Administration route ophthalmic administration
Dosage SYL1801, Low Dose, once daily
Pts 90
Age Adult, Older_Adult
Cohort2: Middle Dose
Administration route ophthalmic administration
Dosage SYL1801, Middle Dose, once daily
Pts 90
Age Adult, Older_Adult
Cohort3: High Dose
Administration route ophthalmic administration
Dosage SYL1801, High Dose, once daily
Pts 90
Age Adult, Older_Adult

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