Basic Information

Gene symbol TNFRSF8 Synonyms CD30, D1S166E, Ki-1 Type of gene protein-coding
Description TNF receptor superfamily member 8

GTO ID GTC3257
Trial ID NCT05634785
Disease Nonseminomatous Germ Cell Tumor | Germ Cell Tumor
Altered gene CD30
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment ATLCAR.CD30
PhasePhase2
Recruitment statusRecruiting
TitleCD30 CAR for CD30+ NSGCT
Year2022
CountryUnited States
Company sponsorUNC Lineberger Comprehensive Cancer Center
Other ID(s)LCCC2048-ATL

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 2E8~5E8 cells/m^2
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph