Gene symbol | EPHA2 | Synonyms | ARCC2, CTPA, CTPP1, CTRCT6, ECK | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1p36.13 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | EPH receptor A2 |
Gene symbol | KRAS | Synonyms | C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2 | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p12.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | KRAS proto-oncogene, GTPase |
GTO ID | GTC3253 |
Trial ID | NCT05631899 |
Disease | Solid Tumor |
Altered gene | KRAS|EPHA2 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-DC cell |
Treatment | KRAS-EphA-2-CAR-DC |
Co-treatment | anti-PD-1 antibody+anti-CTLA4 antibody |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Combination of CAR-DC Vaccine and Anti-PD-1 Antibody in Local Advanced/Metastatic Solid Tumors |
Year | 2022 |
Country | China |
Company sponsor | Chinese PLA General Hospital |
Other ID(s) | CHN-PLAGH-BT-074 |
Cohort1: anti-PD-1 antibody+anti-CTLA4 antibody | |||||||||||
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Cohort2: anti-PD-1 antibody | |||||||||||
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