Basic Information

Gene symbol EPHA2 Synonyms ARCC2, CTPA, CTPP1, CTRCT6, ECK Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description EPH receptor A2

GTO ID GTC3252
Trial ID NCT05631886
Disease Lymphoma
Altered gene EPHA2
Therapeutic/Target gene Target gene
TherapyCAR-DC cell
Treatment TP53-EphA-2-CAR-DC
PhasePhase1
Recruitment statusRecruiting
TitleCombination of CAR-DC Vaccine and Anti-PD-1 Antibody in Malignant Tumors
Year2022
CountryChina
Company sponsorChinese PLA General Hospital
Other ID(s)CHN-PLAGH-BT-075

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 5~10E6 cells/dose, every 8 weeks since Week 5
Donor type Autologous
Pts 10
Age Adult, Older_Adult
Lymph depletion Yes

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