Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3245
Trial ID NCT05625594
Disease Central Nervous System Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleIntracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T-lymphocytes) for the Treatment of Primary Central Nervous System Lymphoma
Year2022
CountryUnited States
Company sponsorCity of Hope Medical Center
Other ID(s)22240|NCI-2022-09152|22240|P30CA033572|R01CA266611

Clinical Result

Cohort 1
Administration route intracerebroventricular injection
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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