Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC3230
Trial ID NCT05611424
Disease Age-Related Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment FT-003
PhasePhase1
Recruitment statusNot Recruiting
TitleAn Open-label, Single-center, Dose-escalation Clinical Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of FT-003 in Subjects With Neovascular Age-related Macular Degeneration
Year2022
CountryChina
Company sponsorFrontera Therapeutics
Other ID(s)FT003WA-1
Vector information
Vectoradeno-associated virus
ConstructAAV-VEGFA
Vector typeadeno-associated virus (AAV) vector
Transgene/Inserted genehuman VEGFA gene

Clinical Result

Cohort 1
Administration route intravitreal injection
Age Adult, Older_Adult

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