Basic Information

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3226
Trial ID NCT05607420
Disease B-Cell Non-Hodgkin's Lymphoma
Altered gene CD20|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment UCAR-T20x22
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleStudy Evaluating UCART20x22 in B-Cell Non-Hodgkin Lymphoma
Year2022
CountrySpain
Company sponsorCellectis S.A.
Other ID(s)UCART20x22_01

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Allogeneic
Pts 80
Age Adult, Older_Adult
Lymph depletion Yes

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