Gene symbol | PPP1R1A | Synonyms | I1, IPP1 | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12q13.2 | dbXrefs | |
Description | protein phosphatase 1 regulatory inhibitor subunit 1A |
GTO ID | GTC3219 |
Trial ID | NCT05598333 |
Disease | Congestive Heart Failure | Non-Ischemic Cardiomyopathy |
Altered gene | PPP1R1A |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | AB-1002|NAN-101 |
Phase | Phase2 |
Recruitment status | Active, Not Recruiting |
Title | A Phase 2, Adaptive, Double-blinded, Placebo Controlled, Randomized, Multi-center Trial to Evaluate the Efficacy, Safety and Tolerability of Intracoronary Infusion of AB-1002 in Adult Subjects With New York Heart Association (NYHA) Class III Heart Failure and Non-ischemic Cardiomyopathy |
Year | 2022 |
Country | United States |
Company sponsor | Asklepios Biopharmaceutical, Inc. |
Other ID(s) | ASK-CHF2-CS201 |
Cohort1: dose level 1 | |||||||
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Cohort2: dose level 2 | |||||||
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