Gene symbol | CLDN18 | Synonyms | SFTA5, SFTPJ | Type of gene | protein-coding | |
Chromosome | 3 | Map location | 3q22.3 | dbXrefs | Entrez:51208 MIM:609210 HGNC:HGNC:2039 Ensembl:ENSG00000066405 AllianceGenome:HGNC:2039 | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | |||||
Description | claudin 18 |
Gene symbol | KLRK1 | Synonyms | CD314, D12S2489E, KLR, NKG2-D, NKG2D | Type of gene | protein-coding | |
Chromosome | 12 | Map location | 12p13.2 | dbXrefs | Entrez:22914 MIM:611817 HGNC:HGNC:18788 Ensembl:ENSG00000213809 AllianceGenome:HGNC:18788 | |
Gene perturbation-related omics dataset | PerturbAtlas | |||||
Description | killer cell lectin like receptor K1 |
GTO ID | GTC3211 |
Trial ID | NCT05583201 |
Disease | Pancreatic Cancer | Solid Tumor | Stomach Cancer |
Altered gene | NKG2D|CLDN18 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | KD-496 |
Phase | Early_Phase1 |
Recruitment status | Recruiting |
Title | NKG2D/CLDN18.2 CAR-T(KD-496) in the Treatment of Advanced NKG2DL+/CLDN18.2+ Solid Tumors |
Year | 2022 |
Country | China |
Company sponsor | jianming xu |
Other ID(s) | KD-496-XJM |
Cohort 1 | |||||||||
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