Basic Information

Gene symbol CLDN18 Synonyms SFTA5, SFTPJ Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description claudin 18

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC3211
Trial ID NCT05583201
Disease Pancreatic Cancer | Solid Tumor | Stomach Cancer
Altered gene NKG2D|CLDN18
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment KD-496
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleNKG2D/CLDN18.2 CAR-T(KD-496) in the Treatment of Advanced NKG2DL+/CLDN18.2+ Solid Tumors
Year2022
CountryChina
Company sponsorjianming xu
Other ID(s)KD-496-XJM

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 18
Age Adult, Older_Adult

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