Gene symbol | GH1 | Synonyms | GH, GH-N, GHB5, GHN, IGHD1A, IGHD1B, IGHD2, hGH-N | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q23.3 | dbXrefs | |
Description | growth hormone 1 |
Gene symbol | LIPF | Synonyms | GL, HGL, HLAL | Type of gene | protein-coding |
Chromosome | 10 | Map location | 10q23.31 | dbXrefs | |
Description | lipase F, gastric type |
Gene symbol | UL128 | Synonyms | None | Type of gene | protein-coding |
Chromosome | - | Map location | NC_006273.2 | dbXrefs | |
Description | contains signal peptide; similar to CC chemokines; complexed with envelope glycoproteins H and L; essential in non-fibroblast cells; involved in cell entry |
Gene symbol | UL130 | Synonyms | None | Type of gene | protein-coding |
Chromosome | - | Map location | NC_006273.2 (176984..177628, complement) | dbXrefs | |
Description | envelope glycoprotein UL130 |
Gene symbol | UL131A | Synonyms | None | Type of gene | protein-coding |
Chromosome | - | Map location | NC_006273.2 (177649..178146, complement) | dbXrefs | |
Description | envelope protein UL131A |
GTO ID | GTC3203 |
Trial ID | NCT05575492 |
Disease | Human Cytomegalovirus Infection |
Altered gene | gB|gH|gL|UL128|UL130|UL131A |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | mRNA-1647 |
Phase | Phase1|Phase2 |
Recruitment status | Active, Not Recruiting |
Title | A Phase 1/2a Open-Label Dose-Ranging and Observer-Blind Placebo-Controlled, Safety and Immunogenicity Study of mRNA-1647 Cytomegalovirus Vaccine in Female and Male Participants 9 to 15 Years of Age and Participants 16 to 25 Years of Age |
Year | 2022 |
Country | Canada|United Kingdom|United States |
Company sponsor | ModernaTX, Inc. |
Other ID(s) | mRNA-1647-P104|2022-001545-20 |
Vector information | |||
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Cohort1: participants 9 to 15 years of age_mRNA-1647 | |||||||
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Cohort2: participants 9 to 15 years of age and 16 to 25 years of age_mRNA-1647 | |||||||
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Cohort3: Placebo | |||||||
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