Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

GTO ID GTC3202
Trial ID NCT05574608
Disease Acute Myeloid Leukemia
Altered gene CD123
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD123 CAR-NK cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleAllogenic CD123-CAR-NK Cells in the Treatment of Refractory/Relapsed Acute Myeloid Leukemia
Year2022
CountryChina
Company sponsorAffiliated Hospital to Academy of Military Medical Sciences

Clinical Result

Cohort 1
Administration route None
Dosage 1E9 cells/kg, 1~2E7 cells/kg
Donor type Allogeneic
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes

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