Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3194
Trial ID NCT05563545
Disease Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD19 CAR-NK cells
PhasePhase1
Recruitment statusCompleted
TitleAnti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory Acute Lymphoblastic Leukemia
Year2022
CountryChina
Company sponsorShanghai Simnova Biotechnology Co., Ltd.

Clinical Result

Cohort 1
Administration route None
Dosage 1E7 cells/kg, 2E7 cells/kg, 3E7 cells/kg
Pts 2
Age Child, Adult, Older_Adult
Lymph depletion Yes

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