Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3191
Trial ID NCT05554939
Disease Non-Hodgkin's Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation2nd
Recruitment statusRecruiting
TitleAllogenic CD19-targeting CAR-γδT Cell Therapy in r/r NHL
Year2022
CountryChina
Company sponsorChinese PLA General Hospital
Other ID(s)CHN-PLAGH-BT-072

Clinical Result

Cohort1: Phase 1
Administration route None
Dosage 2E6 cells/kg, 6E6 cells/kg, 1.8E7 cells/kg
Donor type Allogeneic
Pts 9~12
Age Adult, Older_Adult
Lymph depletion Yes
Cohort2: Phase 2
Administration route None
Dosage RP2D
Donor type Allogeneic
Pts 15~20
Age Adult, Older_Adult
Lymph depletion Yes

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