Basic Information

Gene symbol CLDN18 Synonyms SFTA5, SFTPJ Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description claudin 18

GTO ID GTC3180
Trial ID NCT05539430
Disease Esophageal Cancer | Gastroesophageal Cancer | Pancreatic Cancer | Stomach Cancer
Altered gene CLDN18
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment LB1908
PhasePhase1
Recruitment statusRecruiting
TitleClaudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma
Year2022
CountryUnited States
Company sponsorLegend Biotech USA Inc
Other ID(s)LB1908-1001

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 56
Age Adult, Older_Adult

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