Gene symbol | CLDN18 | Synonyms | SFTA5, SFTPJ | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q22.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | claudin 18 |
GTO ID | GTC3180 |
Trial ID | NCT05539430 |
Disease | Esophageal Cancer | Gastroesophageal Cancer | Pancreatic Cancer | Stomach Cancer |
Altered gene | CLDN18 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | LB1908 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma |
Year | 2022 |
Country | United States |
Company sponsor | Legend Biotech USA Inc |
Other ID(s) | LB1908-1001 |
Cohort 1 | |||||||||
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