Basic Information

Gene symbol C5 Synonyms C5D, C5a, C5b, CPAMD4, ECLZB Type of gene protein-coding
Description complement C5

GTO ID GTC3176
Trial ID NCT05536297
Disease Macular Degeneration | Geographic Atrophy
Altered gene C5
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Avacincaptad pegol|Zimura;ARC1905
PhasePhase3
Recruitment statusActive, Not Recruiting
TitleAn Open-label Extension (OLE) Phase 3 Trial to Assess the Safety of Intravitreal Administration of Avacincaptad Pegol (Complement C5 Inhibitor) in Patients With Geographic Atrophy Who Previously Completed Phase 3 Study ISEE2008 (GATHER2)
Year2022
CountryArgentina|Canada|Colombia|Croatia|Czechia|France|Germany|Hungary|Israel|Italy|Latvia|Spain|United States
Company sponsorIVERIC bio, Inc.
Other ID(s)ISEE2009

Clinical Result

Cohort 1
Administration route intravitreal injection
Dosage Avacincaptad pegol, 2 mg, monthly from Month 1 to Month 17
Pts 278
Age Adult, Older_Adult

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