Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3168
Trial ID NCT05523661
Disease Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
Co-treatment Dasatinib
PhasePhase1
Recruitment statusRecruiting
TitleDasatinib Plus Anti-CD19/CD22 Bispecific CAR-T Cell Therapy for Elderly Ph-positive ALL Patients
Year2022
CountryChina
Company sponsorShanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Other ID(s)HRAIN01-ALL02-POC

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 15
Age Adult, Older_Adult
Lymph depletion Yes

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