Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol GPRC5D Synonyms None Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description G protein-coupled receptor class C group 5 member D

GTO ID GTC3153
Trial ID NCT05509530
Disease Multiple Myeloma
Altered gene BCMA|GPRC5D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA/GPRC5D CAR-T cells
PhasePhase2
Recruitment statusRecruiting
TitleSafety and Efficacy of Anti-BCMA/GPRC5D CAR-T Cell Therapy in Treating Relapsed and Refractory Multiple Myeloma(rr/MM)
Year2022
CountryChina
Company sponsorXuzhou Medical University
Other ID(s)XYFY2022-KL118-01

Clinical Result

Cohort 1
Administration route None
Dosage 1~2E6 cells/kg
Donor type Autologous
Pts 30
Age Adult, Older_Adult
Lymph depletion Yes

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