Basic Information

Gene symbol FOLH1 Synonyms FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP Type of gene protein-coding
Description folate hydrolase 1

GTO ID GTC3147
Trial ID NCT05489991
Disease Castration-Resistant Prostate Carcinoma
Altered gene PSMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment TmPSMA-02
Generation2nd
PhasePhase1|Phase2
Recruitment statusActive, Not Recruiting
TitleA Study of TmPSMA-02 Chimeric Antigen Receptor (CAR) T-cells in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)
Year2022
CountryUnited States
Company sponsorTmunity Therapeutics
Other ID(s)TmPSMA-0201
Vector information
Vectorlentivirus
ConstructscFv-CD2-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 114
Age Adult, Older_Adult
Lymph depletion Yes

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