Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3140
Trial ID NCT05480449
Disease Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment huCART19
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleAutologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)
Year2022
CountryUnited States
Company sponsorStephan Grupp MD PhD
Other ID(s)22-019978|22CT011
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route None
Dosage <50kg: 5E6 cells/kg, >50kg: 2.5E8 cells
Donor type Autologous
Pts 89
Age Child, Adult
References PMID: 37607096

Relationship Graph

Overview of Knowledge Graph