| Gene symbol | H3-3A | Synonyms | BRYLIB1, H3-3B, H3.3A, H3F3, H3F3A | Type of gene | protein-coding |
| Chromosome | 1 | Map location | 1q42.12 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | ||||
| Description | H3.3 histone A | ||||
| GTO ID | GTC3138 |
| Trial ID | NCT05478837 |
| Disease | Diffuse Midline Glioma |
| Altered gene | H3-3A |
| Therapeutic/Target gene | Target gene |
| Therapy | TCR-T cell |
| Treatment | KIND T cells |
| HLA | HLA-A*02:01 |
| Phase | Phase1 |
| Recruitment status | Recruiting |
| Title | PNOC018 A Phase 1 Clinical Trial of Autologous T Cells Expressing a TCR Specific for H3.3K27M With Inhibition of Endogenous TCR (KIND T Cells) in HLA-A*0201-positive Participants With Newly Diagnosed H3.3K27M-positive Diffuse Midline Gliomas |
| Year | 2022 |
| Country | United States |
| Company sponsor | University of California, San Francisco |
| Other ID(s) | 210813|NCI-2022-05420|PICI0029 |
| Cohort 1 | |||||||||
|
|||||||||