Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3133
Trial ID NCT05474885
Disease Systemic Lupus Erythematosus
Altered gene BCMA|CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA/CD19 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleBCMA-CD19 cCAR T Cell Treatment of Relapsed/Refractory Systemic Lupus Erythematosus (SLE)
Year2022
CountryChina
Company sponsoriCell Gene Therapeutics
Other ID(s)ICG180-001
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 15
Age Adult, Older_Adult
Lymph depletion Yes

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