Gene symbol | KRT31 | Synonyms | HA1, Ha-1, KRTHA1, hHa1 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q21.2 | dbXrefs | |
Description | keratin 31 |
Gene symbol | KRT32 | Synonyms | HA2, HKA2, KRTHA2, hHa2 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q21.2 | dbXrefs | |
Description | keratin 32 |
GTO ID | GTC3131 |
Trial ID | NCT05473910 |
Disease | Myelodysplastic Syndrome | Leukemia |
Altered gene | HA1|HA2 |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | TSC-100|TSC-101 |
HLA | HLA-A*02:01 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Controlled Multi-Arm Ph1 Study Evaluating the Safety and Feasibility of TCR Engineered Donor TCells Targeting HA1 (TSC-100) or HA2 (TSC-101) in HLA-A0201 Positive Patients Undergoing Haploidentical Allogeneic Stem Cell Transplantation |
Year | 2022 |
Country | United States |
Company sponsor | TScan Therapeutics, Inc. |
Other ID(s) | TSCAN-001 |
Cohort1: HA-1 positive | |||||||||
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Cohort2: HA-2 positive | |||||||||
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