Basic Information

Gene symbol CLDN18 Synonyms SFTA5, SFTPJ Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description claudin 18

GTO ID GTC3129
Trial ID NCT05472857
Disease Stomach Cancer | Ovarian Carcinoma | Pancreatic Cancer | Gastroesophageal Adenocarcinoma
Altered gene CLDN18
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CLDN18.2 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleClinical Study of CLDN18.2-targeting CAR T Cells in Advanced Solid Tumors With Positive CLDN18.2 Expression
Year2022
CountryChina
Company sponsorSuzhou Immunofoco Biotechnology Co., Ltd
Other ID(s)IMC002-CT01

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 30
Age Adult, Older_Adult

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