Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3125
Trial ID NCT05470777
Disease B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
Generation2nd
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleCD22/CD19 CAR-T and Auto-HSCT Sandwich Strategy as Consolidation Therapy for B-ALL
Year2022
CountryChina
Company sponsorThe First Affiliated Hospital of Soochow University
Other ID(s)SZCART02

Clinical Result

Cohort 1
Administration route None
Dosage 1E6 cells/kg
Donor type Autologous
Pts 35
Age Child, Adult, Older_Adult

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