Basic Information

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC3123
Trial ID NCT05467254
Disease Acute Myeloid Leukemia
Altered gene CLL1|CD33
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD33/CLL1 CAR-T cells
PhasePhase1
Recruitment statusNot Recruiting
TitleEvaluate the Safety and Efficacy of CLL1+CD33 CAR-T in Patients With R/R AML
Year2022
CountryChina
Company sponsorZhejiang University
Other ID(s)BG-CT-22-002(CLL1+CD33)

Clinical Result

Cohort 1
Administration route None
Dosage 3E6 cells/kg, 6E6 cells/kg, 9E6 cells/kg
Donor type Autologous
Pts 20
Age Child, Adult, Older_Adult
Lymph depletion Yes

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