Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

GTO ID GTC3114
Trial ID NCT05457010
Disease Acute Myeloid Leukemia | Myelodysplastic Syndrome
Altered gene CD123
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment SPRX002
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitlePhase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS
Year2022
CountryUnited States
Company sponsorArcellx, Inc.
Other ID(s)ARC-201
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 24
Age Adult, Older_Adult

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