Gene symbol | MSLN | Synonyms | MPF, SMRP | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | mesothelin |
GTO ID | GTC3108 |
Trial ID | NCT05451849 |
Disease | Lung Non-Small Cell Carcinoma | Colorectal Carcinoma | Peritoneal Mesothelioma | Mesothelioma | Triple-Receptor Negative Breast Cancer | Malignant Mesothelioma | Ovarian Cancer | Ovarian Melanoma | Pancreatic Cancer | Ovarian Serous Cystadenocarcinoma | Pancreatic Adenocarcinoma | Colorectal Cancer | Cholangiocarcinoma | Mesotheliomas Pleural |
Altered gene | MSLN |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | TC-510|MSLN TCR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | A Phase 1/2 Single Arm Open-Label Clinical Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer |
Year | 2022 |
Country | United States |
Company sponsor | TCR2 Therapeutics |
Other ID(s) | TCR2-21-01 |
Cohort 1 | |||||||||
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