Basic Information

Gene symbol MUSK Synonyms CMS9, FADS, FADS1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description muscle associated receptor tyrosine kinase

GTO ID GTC3107
Trial ID NCT05451212
Disease Myasthenia Gravis
Altered gene MuSK
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment MuSK-CAART
PhasePhase1
Recruitment statusRecruiting
TitleOpen-label Study to Evaluate the Safety of Various Dosing Regimens of MuSK-CAART for MuSK Myasthenia Gravis
Year2022
CountryUnited States
Company sponsorCabaletta Bio
Other ID(s)CAB-MuSK-101

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 24
Age Adult, Older_Adult
Lymph depletion Yes/No

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