Basic Information

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

GTO ID GTC3105
Trial ID NCT05445765
Disease Hematologic Cancer | Acute Myeloid Leukemia
Altered gene CD33
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD33 CAR-T cells
PhasePhase1
Recruitment statusNot Recruiting
TitleAnti-CD33 CAR-T Cells for the Treatment of Relapsed/Refractory CD33+ Acute Myeloid Leukemia
Year2022
CountryChina
Company sponsoriCell Gene Therapeutics
Other ID(s)ICG165-001
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 10
Age Child, Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph