Basic Information

Gene symbol FLT3 Synonyms CD135, FLK-2, FLK2, STK1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description fms related receptor tyrosine kinase 3

GTO ID GTC3103
Trial ID NCT05445011
Disease Acute Myeloid Leukemia
Altered gene FLT3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment TAA05
PhasePhase1
Recruitment statusRecruiting
TitleAnti-FLT3 CAR-T Cell (TAA05 Cell Injection) in the Treatment of Relapsed / Refractory Acute Myeloid Leukemia
Year2022
CountryChina
Company sponsorWuhan Union Hospital, China
Other ID(s)Anti-FLT3 CAR-T Cell

Clinical Result

Cohort 1
Administration route None
Dosage 1E8 cells, 2E8 cells, 4E8 cells
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes

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