Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3100
Trial ID NCT05442515
Disease Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | B-Cell Lymphoma | B-Cell Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleCD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Year2022
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)10000324|000324-C

Clinical Result

Cohort 1
Administration route None
Pts 146
Age Child, Adult

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