Gene symbol | KRAS | Synonyms | C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2 | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p12.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | KRAS proto-oncogene, GTPase |
GTO ID | GTC3097 |
Trial ID | NCT05438667 |
Disease | Pancreatic Cancer |
Altered gene | KRAS |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | KRAS TCR-T cells |
HLA | HLA-A*11:01 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Prospective, One Arm Clinical Study on the Safety, Efficacy and Pharmacokinetics of KRAS Mutant Antigen Specific TCR-T Cells in the Treatment of Advanced Pancreatic Cancer |
Year | 2022 |
Country | China |
Company sponsor | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
Other ID(s) | [2022]01-01 |
Cohort 1 | |||||||||||
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