Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3088
Trial ID NCT05432882
Disease B-Cell Malignancy
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment bi-4SCAR CD19/22 T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleCD19/22 Bi-specific CAR-T Cell Therapy
Year2022
CountryChina
Company sponsorShenzhen Geno-Immune Medical Institute
Other ID(s)GIMI-IRB-22007
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route None
Pts 60
Age Child, Adult, Older_Adult

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