Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3081
Trial ID NCT05429905
Disease Acute Lymphoblastic Leukemia
Altered gene CD22|CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T2219.1
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleDual Anti-CD22/CD19 Chimeric Antigen Receptor-directed T Cells (CART2219.1) for Relapsed Refractory B-Lineage Leukaemia
Year2022
CountrySingapore
Company sponsorKK Women's and Children's Hospital
Other ID(s)CART2219-1.0

Clinical Result

Cohort 1
Administration route None
Dosage 0.4E6 cells/kg, 1E6 cells/kg, 2.5E6 cells/kg
Pts 48
Age Child, Adult, Older_Adult

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