Basic Information

Gene symbol S Synonyms E2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description spike glycoprotein

GTO ID GTC3067
Trial ID NCT05415267
Disease COVID-19
Altered gene S
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment COVID-19 mRNA Vaccine
Co-treatment diphtheria and tetanus toxoids (adsorbed) vaccine
PhasePhase3
Recruitment statusRecruiting
TitleComparison of Immunity-boosting Regimens for COVID-19 Upon Initiation of Immunosuppressive Therapy
Year2023
CountryAustralia
Company sponsorKirby Institute
Other ID(s)CIRCUIT Study

Clinical Result

Cohort1: COVID-19 vaccine_at week 0_dT vaccine_at week 24
Administration route None
Dosage COVID-19 vaccine, at week 0; dT vaccine, at week 24
Pts 140
Age Adult, Older_Adult
Cohort2: COVID-19 vaccine_at week 24_dT vaccine_at week0
Administration route None
Dosage COVID-19 vaccine, at week 24; dT vaccine, at week 0
Pts 140
Age Adult, Older_Adult
Cohort3: COVID-19 vaccine_at week 0
Administration route None
Dosage COVID-19 vaccine, at week 0
Pts 20
Age Adult, Older_Adult
Cohort4: COVID-19 vaccine_at week 24
Administration route None
Dosage COVID-19 vaccine, at week 0
Pts 20
Age Adult, Older_Adult

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