Gene symbol | AXL | Synonyms | ARK, AXL3, JTK11, Tyro7, UFO | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | AXL receptor tyrosine kinase |
Gene symbol | CLDN6 | Synonyms | None | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.3 | dbXrefs | |
Description | claudin 6 |
Gene symbol | GPC3 | Synonyms | DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 | Type of gene | protein-coding |
Chromosome | X | Map location | Xq26.2 | dbXrefs | |
Description | glypican 3 |
GTO ID | GTC3064 |
Trial ID | NCT05410717 |
Disease | Endometrial Cancer | Testis Refractory Cancer | Ovarian Cancer |
Altered gene | CLDN6|GPC3|MESO|AXL |
Therapeutic/Target gene | Target gene |
Therapy | CAR-NK cell |
Treatment | CLDN6/GPC3/MESO/AXL CAR-NK cells |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | CLDN6-CAR-NK Cell Therapy for Advanced Solid Tumors |
Year | 2022 |
Country | China |
Company sponsor | Second Affiliated Hospital of Guangzhou Medical University |
Other ID(s) | ZCARNK-017 |
Cohort 1 | |||||||
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