Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3059
Trial ID NCT05400109
Disease Non-Hodgkin's Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment UF-KURE19 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleEvaluate the Safety of UF-KURE19 Cells in Non-Hodgkin Lymphomas
Year2022
CountryUnited States
Company sponsorJames Michael Martin
Other ID(s)CASE2422
Vector information
Vectorlentivirus

Clinical Result

Cohort1: Participants ≥50 kg
Administration route None
Dosage 8.5E6 cells, 17.5E6 cells
Donor type Autologous
Age Adult, Older_Adult
Lymph depletion Yes
Cohort2: Participants <50 kg
Administration route None
Dosage 5.5E6 cells, 11.5E6 cells
Donor type Autologous
Age Adult, Older_Adult
Lymph depletion Yes

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