Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC3049
Trial ID NCT05396885
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Anitocabtagene Autoleucel
Generation2nd
PhasePhase2
Recruitment statusRecruiting
TitleStudy of CART-ddBMCA in Relapsed or Refractory Multiple Myeloma (iMMagine-1)
Year2022
CountryUnited States
Company sponsorArcellx, Inc.
Other ID(s)ARC-112A
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1.05~1.25E8 cells
Donor type Autologous
Pts 110
Age Adult, Older_Adult

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