Basic Information

Gene symbol CLDN18 Synonyms SFTA5, SFTPJ Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description claudin 18

GTO ID GTC3046
Trial ID NCT05393986
Disease Gastroesophageal Adenocarcinoma | Gastric Adenocarcinoma | Pancreatic Cancer
Altered gene CLDN18
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CT048
PhasePhase1
Recruitment statusRecruiting
TitleClaudin18.2-redirected Chimeric Antigen Receptor T Cells With Co-expression of Cytokines in Solid Tumors
Year2022
CountryChina
Company sponsorPeking University
Other ID(s)CT048-CG4001

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 63
Age Adult, Older_Adult
Lymph depletion Yes

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