Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC3045
Trial ID NCT05393804
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Abecma|bb2121|BMS-986395|Idecabtagene vicleucel|ide-cel
Location approved US, Canada, EU, UK, Japan, Israel, Switzerland
Generation2nd
PhasePhase2
Recruitment statusRecruiting
TitleA Study of Whether Ide-cel (bb2121) Can Be Made From People With Multiple Myeloma Who Have Had a Hematopoietic Cell Transplant
Year2022
CountryUnited States
Company sponsorMemorial Sloan Kettering Cancer Center
Other ID(s)22-118
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 300~460E6 cells
Donor type Autologous
Pts 32
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph