Basic Information

Gene symbol IL12A Synonyms CLMF, IL-12A, NFSK, NKSF1, P35 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description interleukin 12A

Gene symbol IL12B Synonyms CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2 Type of gene protein-coding
Description interleukin 12B

GTO ID GTC3043
Trial ID NCT05392699
Disease Advanced Solid Tumor
Altered gene IL-12A|IL-12B
Therapeutic/Target gene Therapeutic gene
TherapymRNA
Treatment ABOD2011
PhasePhase1
Recruitment statusRecruiting
TitleAn Open-blind Dose Escalation Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ABOD2011 in Patients With Advanced Solid Tumors Progressed After Standard Systemic Therapy
Year2022
CountryChina
Company sponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences
Other ID(s)ABOD2011-001
Vector information
Vectorlipid nanoparticle

Clinical Result

Cohort1: ABOD2011_single dose
Administration route intratumoral injection
Dosage ABOD2011, single dose
Age Adult, Older_Adult
Cohort2: ABOD2011_multiple dose
Administration route intratumoral injection
Dosage ABOD2011, multiple dose
Age Adult, Older_Adult

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