Gene symbol | IL12A | Synonyms | CLMF, IL-12A, NFSK, NKSF1, P35 | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q25.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | interleukin 12A |
Gene symbol | IL12B | Synonyms | CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2 | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5q33.3 | dbXrefs | |
Description | interleukin 12B |
GTO ID | GTC3043 |
Trial ID | NCT05392699 |
Disease | Advanced Solid Tumor |
Altered gene | IL-12A|IL-12B |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA |
Treatment | ABOD2011 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | An Open-blind Dose Escalation Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ABOD2011 in Patients With Advanced Solid Tumors Progressed After Standard Systemic Therapy |
Year | 2022 |
Country | China |
Company sponsor | Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
Other ID(s) | ABOD2011-001 |
Vector information | |||
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Cohort1: ABOD2011_single dose | |||||||
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Cohort2: ABOD2011_multiple dose | |||||||
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