Basic Information

Gene symbol KRAS Synonyms C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description KRAS proto-oncogene, GTPase

GTO ID GTC3039
Trial ID NCT05389514
Disease Epithelial Cancer
Altered gene KRAS
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment KRAS G12V TCR-T cells
HLAHLA-DRB1*07:01
Recruitment statusAvailable
TitleIntermediate-size Patient Population IND for Treatment of KRAS G12V-mutant Tumors With Gene-engineered KRAS G12V-reactive T Cells
Year2022
CountryUnited States
Company sponsorProvidence Health & Services
Other ID(s)2020000471

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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