Gene symbol | KRAS | Synonyms | C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2 | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p12.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | KRAS proto-oncogene, GTPase |
GTO ID | GTC3039 |
Trial ID | NCT05389514 |
Disease | Epithelial Cancer |
Altered gene | KRAS |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | KRAS G12V TCR-T cells |
HLA | HLA-DRB1*07:01 |
Recruitment status | Available |
Title | Intermediate-size Patient Population IND for Treatment of KRAS G12V-mutant Tumors With Gene-engineered KRAS G12V-reactive T Cells |
Year | 2022 |
Country | United States |
Company sponsor | Providence Health & Services |
Other ID(s) | 2020000471 |
Cohort 1 | |||||||||
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